It’s no secret that every athlete has a different reaction to taking steroids. On one side of the barricades are bodybuilders whose use and intake of steroids does not cause health problems and sometimes even improves. They easily build muscle, get rid of excess fat and just feel much better. And on the other hand, athletes who are affected only negatively by anabolic steroids. And bruises under the eyes, itching and loose hair are half the trouble because some bodybuilders face such problems that one would not wish the enemy. If you want to protect yourself when buying steroids, you should first consult with an expert here

Anabolic steroid use and androgen receptor gene polymorphism

All of these differences in response to anabolic steroid intake have been interpreted by various experts, and many have been successful in studying this issue. The high density of androgen receptors in our muscle tissues, directly affects the intake of anabolic steroids, that is, the effectiveness of steroid-type drugs. However, if the opposite is true for your body, i.e., the receptor density in your muscles is low and the rest of your body is high, then you should most likely expect to experience some kind of side effects.

Another important component, is the Metabolism of the steroid, or its breakdown. For example, testosterone, in its breakdown, is able to convert into many other hormones, such as estrogens. And the higher the rate of its conversion (steroid metabolism), the greater the chance of side effects. That is, the anabolic effect is less, and the side effects are greater.

There is a perception that androgen receptors in humans are the same, but this is not true, and therefore the reactions after taking anabolic steroids are different for everyone. There are no people who have a completely identical set of androgen receptors, in principle it is very similar to fingerprints here. Scientifically, the differences in androgen receptors are caused by polymorphisms or modifications.

CAG and steroid exposure

The gene responsible for androgen receptor reproduction is polymorphic in nature. The reason for this is the varying number of repeating CAG (cytosine, adenine, guanine). In most people, both experienced athletes and beginners, the number of CAG repeats varies from 6 to 39 (i.e., in the gene responsible for coding receptors, the number of CAG repeats ranges from 6 to 39, so it seems clearer). Up to 23 CAG repeats are considered short repeats, over 23 are considered high repeats.

People with short repeats are most sensitive to the androgenic effects of AAS. Conversely, people with a high number of repeats are less sensitive to steroid exposure. Determining your number of repeats is easy, if you were plagued by acne or increased hair growth as a child, then you have short repeats. And if you haven’t encountered such problems, then you have long repeats of the CAG triplet. And it’s up to you to decide whether that’s good or bad. If you want help choosing steroids, visit